SYNOPSIS:

bOObs: The War on Women’s Breasts investigates the controversy swirling around the breast cancer screening test mammography. Over a 30-year period, mammogram’s use led to over-diagnosing 1.3 million U.S. women, resulting in needless treatments for breast cancers that otherwise may not have spread.

*The information provided here is not supported by any specific physician or medical entity. The information provided is a collection of research. Please contact your medical provider for treatment options. 

 

Medical 
Studies

Idiopathic Granulomatous Mastitis has no known origin and no known cure. Here you will find a compilation of recent case studies for your reading. 

*The information provided here is not supported by any specific physician or medical entity. The information provided is a collection of research. Please contact your medical provider for treatment options. 

 

June 2020
A Case of Chronic Granulomatous Mastitis Caused by Corynebacterium kroppenstedtii.

ANNEKA HUTTON, MD; SAMMER M. ELWASILA, MD; AND GABRIEL SANDKOVSKY, MD

February 2020
Granulomatous lobular mastitis: Clinical update and case study

The aim of this article is to provide a clinical update and case study for general practitioners, who are usually the first to see the patient.

February 5, 2020 
Idiopathic Granulomatous Mastitis-A Mystery Yet to be Unraveled: A Case Series and Review of Literature

Mathew Thomas V, Alexander S, Bindal P, et al. (February 05, 2020) Idiopathic Granulomatous Mastitis-A Mystery Yet to be Unraveled: A Case Series and Review of Literature. Cureus 12(2): e6895. doi:10.7759/cureus.6895.

We present a case series of two cases of IGM, which were successfully treated.

April 2020 

Granulomatous Mastitis: Pathological Findings Can Guide Clinical Management

Continuing Medical Education (CME) Session on Granulomatous Mastitis by Maldives Association of Surgeons, hosted by Tree Top Hospital.

November 2019
What is Granulomatous Mastitis?

Presented by Breast and Colorectal Surgeon, Dr. Ritu Khare

February 2019
How To Identify Your 16S rRNA Sequences

This quick tutorial shows you how to use BLAST to identify your 16S sequences, and provides a few BLAST search tips. NCBI provides a curated database of 16S sequences from well-supported type material that is a subset of the BLAST nt database.

October 2019

Corynebacterium kroppenstedtii: a challenging culprit in breast abscesses and granulomatous mastitis

December 2018

Granulomatous Mastitis: A Therapeutic and Diagnostic Challenge

December 2014

Effect of topical steroid treatment on idiopathic granulomatous mastitis: clinical and radiologic evaluation

 

Root

Causes

There are currently various theories of the causes of IGM; here you will find a compilation of these theories. ​

*The information provided here is not supported by any specific physician or medical entity. The information provided is a collection of research. Please contact your medical provider for treatment options. 

 

What causes Idiopathic Granuloma Mastitis?

Primary presentation of any of these conditions as mastitis is very rare and in many cases probably predisposed by other breast or systemic conditions. Although granulomatous mastitis is easily confused with cancer it is a completely benign (non-cancerous) condition. Treatment is radically different for idiopathic granulomatous mastitis and other granulomatous lesions of the breast, so the precise diagnosis is therefore very important.

What is Corynebacterium?

Corynebacterium is a genus of bacteria that are Gram-positive and aerobic. They are bacilli, and in some phases of life they are, more particularly, club-shaped, which inspired the genus name.

What is 16S rRNA Gene Sequencing?

16S rRNA gene sequencing is generally used for identification and classification microbes within complex biological mixtures such as environmental and gut samples.

 

Potential Medications

There is currently no cure for IGM, only a variety of treatment options as suggested through research. 

*The information provided here is not supported by any specific physician or medical entity. The information provided is a collection of research. Please contact your medical provider for treatment options. 

 

What is Prednisone?

Prednisone is used to treat conditions such as arthritisblood disordersbreathing problems, severe allergiesskin diseases, cancereye problems, and immune system disorders. Prednisone belongs to a class of drugs known as corticosteroids. It decreases your immune system's response to various diseases to reduce symptoms such as swelling and allergic-type reactions.

Methotrexate and GM

Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis that has not responded to other treatments. It may also be used to control juvenile rheumatoid arthritisMethotrexate belongs to a class of drugs known as antimetabolites. It works by slowing or stopping the growth of cancer cells and suppressing the immune system.

Doxycycline for treating GM

Doxycycline belongs to the class of antibiotics known as tetracyclines. At this low dosage, this medication does not treat bacterial infections, but it may help to prevent breakdown of gum tissue. Antibiotics do not work for viral infections (such as common coldflu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

Kenalog Injection

Depending on your product, this medication may be given by injecting into different locations such as a muscle (intramuscularly), a skin lesion (intradermally), or a joint (intra-articularly). Injections are usually given by a trained healthcare professional. If you are giving yourself intramuscular injection, you will be taught by your healthcare professional on how to properly use this medication. If any of the information is unclear, consult your healthcare professional.

AIP (Autoimmune Protocol) Diet

Many people who have followed the AIP diet report improvements in the way they feel, as well as reductions in common symptoms of autoimmune disorders, such as fatigue and gut or joint pain. Yet, while research on this diet is promising, it’s also limited.

*The information provided here is not supported by any specific physician or medical entity. The information provided is a collection of research. Please contact your medical provider for treatment options.